Sugary soda has highest sugar content and zero nutritional value.
By Brigham Young University
A massive new study reveals that the source of sugar makes all the difference. While sugary drinks like soda and even fruit juice sharply increase the risk of type 2 diabetes, sugars in solid foods—especially nutrient-rich ones—may actually be less harmful or even protective. The findings challenge long-standing dietary assumptions and suggest it’s time to rethink how we talk about sugar and health.
For years, we’ve heard that sugar is one of the main drivers
behind the global rise in type 2 diabetes. But new research from Brigham Young
University is changing the way we look at sugar. According to the
findings, where your sugar comes from matters just as much as how much you
consume.
In the most extensive analysis of its kind, researchers from
BYU and institutions in Germany examined data from over 500,000 people across
multiple continents. Their discovery? Sugars from drinks like soda and even
fruit juice were consistently linked to a higher risk of developing type 2
diabetes (T2D). Surprisingly, sugars from other sources did not show this same
risk. In fact, some were even linked to a lower risk.
Why Drinking Sugar Is Riskier
“This is the first study to draw clear dose-response
relationships between different sugar sources and type 2 diabetes risk,” said
Karen Della Corte, lead author and BYU nutritional science professor. “It
highlights why drinking your sugar—whether from soda or juice—is more
problematic for health than eating it.”
Even after accounting for factors like body mass index,
overall calorie intake, and several other lifestyle risk factors, the
differences were striking:
- With
each additional 12-oz serving of sugar-sweetened beverages (i.e., soft
drinks, energy drinks, and sports drinks) per day, the risk for developing
T2D increased by 25%. This strong relationship showed that the increased
risk began from the very first daily serving with no minimum threshold
below which intake appeared to be safe.
- With
each additional 8-oz serving of fruit juice per day (i.e., 100% fruit
juice, nectars and juice drinks), the risk for developing T2D increased by
5%.
- The
above risks are relative not absolute. For example, if the average
person’s baseline risk of developing T2D is about 10%, four sodas a day
could raise that to roughly 20%, not 100%.
- Comparatively, 20 g/day intakes of total sucrose (table sugar) and total sugar (the sum of all naturally occurring and added sugars in the diet) showed an inverse association with T2D, hinting at a surprising protective association.
The Metabolic Consequences of Liquid Sugar
Why drinking sugar would be more problematic than eating
sugar may come down to the differing metabolic effects. Sugar-sweetened
beverages and fruit juice supply isolated sugars, leading to a greater glycemic
impact that would overwhelm and disrupt liver metabolism, thereby increasing
liver fat and insulin resistance.
On the other hand, dietary sugars consumed in or added to
nutrient-dense foods, such as whole fruits, dairy products, or whole grains, do
not cause metabolic overload in the liver. These embedded sugars elicit slower
blood glucose responses due to accompanying fiber, fats, proteins, and other
beneficial nutrients.
Fruit Juice Isn’t a Free Pass
Fruit juice, even with some vitamins and nutrients, is much
less beneficial. Because of its high and concentrated sugar content, the
researchers conclude that fruit juice is a poor substitute for whole fruits,
which provide more fiber to support better blood glucose regulation.
“This study underscores the need for even more stringent
recommendations for liquid sugars such as those in sugar-sweetened beverages
and fruit juice, as they appear to harmfully associate with metabolic health,”
Della Corte said. “Rather than condemning all added sugars, future dietary
guidelines might consider the differential effects of sugar based on its source
and form.”
Reference: “Dietary Sugar Intake and Incident Type 2
Diabetes Risk: A Systematic Review and Dose-Response Meta-Analysis of
Prospective Cohort Studies” by Karen A Della Corte, Tyler Bosler, Cole McClure,
Anette E Buyken, James D LeCheminant, Lukas Schwingshackl and Dennis Della
Corte, 21 March 2025, Advances in Nutrition.
DOI:
10.1016/j.advnut.2025.100413
BYU professors James LeCheminant and Dennis Della Corte, as
well as students Tyler Bosler and Cole McClure, were also co-authors on the
study, recently published in the journal Advances in Nutrition.