mRNA vaccine development to fight cancer
By Olivia
Newton-John Cancer Research Institute
Edited by Sadie Harley, reviewed by Robert Egan
A study by Australian researchers compared three mRNA-LNP
vaccine platforms in human blood samples, generating findings that could
advance cancer treatment and vaccine design.
Photo by Spencer Davis on Unsplash
mRNA-lipid nanoparticles (LNPs) transformed the way that
vaccines are delivered to humans when they became widely used during the
COVID-19 pandemic.
mRNA-LNPs
are tiny parcels, ~800 times smaller than the width of a human hair, made of
fatty acids (lipids) and containing cargo (messenger RNA) that needs to be
delivered inside the body to generate a treatment response (for example,
immunity to a virus).
Today, researchers around the world are investigating
mRNA-LNPs as candidates for "cancer
vaccines" that would deliver mRNA cargo to boost the patient's immune
system and empower it to kill cancer more effectively.

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