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Wednesday, July 15, 2026

How to prevent New World screwworm infestations in cats and dogs

Protect your pet from Trump-Musk screw-up

Liz Szabo, MA

Although the New World screwworm (NWS) mainly endangers livestock, the parasitic flies can also attack and kill pets.

Two of the 34 animals sickened by NWS since early June are dogs. One dog was infested in New Mexico, and a second dog was sickened in Texas. 

Most animals in the United States have a low risk of being affected. Pets are at elevated risk if they live in areas with documented NWS cases, including Lea County, New Mexico, and the Texas counties of Brewster, Crocket, Edwards, Gillespie, Jim Hogg, LaSalle, Medina, Pecos, Sutton, Terrell, Tom Green, Uvalde, and Zavala.

Something out of a horror movie

Screwworm infestations sound like something out of a horror movie: They occur when the adult fly Cochliomyia hominivorax lays eggs in a wound or body opening of a warm-blooded animal. When the eggs hatch, they devour the animal’s flesh. 

Infestations can cause severe tissue damage, serious infections, and death, especially if not detected and treated early.

For many pet owners, the thought of screwworms attacking their dogs and cats is horrifying.

The good news is that there are ways to prevent and treat infestations— and your dogs and cats may already be using them.

Preventing infestations with medication

Medications that prevent fleas and ticks are a first line of defense against screwworm. By preventing itchy bites, these medications prevent dogs and cats from scratching themselves and creating a wound in which the adult flies can lay their eggs, said Kate Elden, DVM, chief medical officer at Dutch, a company that offers telehealth visits for animals.

In addition to killing fleas and ticks, these medications—called isoxazolines—also kill screwworm larvae, Elden said. While they won’t prevent the screwworm fly from laying eggs in a wound, these anti-parasitic drugs will prevent the devastating injuries caused by larvae.This class of drugs includes lotilaner, afoxalaner, fluralaner, and sarolaner. 

The Food and Drug Administration (FDA) has issued emergency use authorizations for three treatments for dogs and cats, including two isoxazolines.

If your pet is on one of those products, they are not going to get screwworm.

Authorized products include NexGard (afoxolaner) chewable tablets for dogs and puppies, and NexGard Combo (esafoxolaner, eprinomectin, and praziquantel topical solution) for cats and kittens. Both treatments are available by prescription and protect pets from fleas and ticks. NexGard Combo also protects cats from worms. 

The FDA also authorized Credelio for dogs and puppies and Credelio Cat (lotilaner) for kittens and cats. Both kill fleas and ticks and are sold as chewable tablets, available by prescription.

Although the FDA approved these drugs to treat NWS infestations, they will likely prevent infestations as well, wrote Scott Weese, DVM, a veterinary internal medicine specialist and the chief of infection control at University of Guelph’s Ontario Veterinary College in Canada, on the Worms & Germs blog.

Elden recommends that all pets take medication to prevent fleas, ticks, and heartworm, no matter where they live.

“You should have your dog or cat on an isoxazoline,” Elden said. “If your pet is on one of those products, they are not going to get screwworm.”

Additional treatments for screwworm

The FDA also approved nitenpyram, sold as Capstar or CapAction and available without a prescription, as a treatment for dogs, puppies, cats, and kittens infested by screwworm.

Nitenpyram, which begins killing adult fleas within 30 minutes, is used to get rid of fleas quickly, such as after a dog romps in the woods and returns covered in bugs. The drug’s effects last only 24 hours.

In his blog, Weese noted that a small study found nitenpyram to be 100% effective at killing screwworms within 24 hours of administering a standard dose in naturally infested dogs.

After treatment, a veterinarian may still need to physically remove any remaining live or dead larvae, according to the FDA. The agency cautions pet owners against trying to remove the larvae themselves, to reduce the risk of infection or damaging tissue. Pet owners should ask their vet about wound care and how to reduce the risk of new infestations. 

Veterinarians recommend that people who live near areas with screwworm outbreaks inspect any pets that go outdoors once a day. Most vets interviewed told CIDRAP News that it’s not necessary to keep pets indoors, unless they have an open wound.

Now's not a good time to let your dog just be outside hanging out with all the livestock and the flies, if you can avoid it.

Elden is more cautious. “Even if I had a healthy dog, I would consider keeping them inside unless I was just going for walks,” she said. “I'm not naturally an alarmist, so I don't want people to start panicking. But if this were my own pet, knowing what I know about screwworm, it’s the most reasonable thing to do.”

For people who live in affected areas of Texas and New Mexico, “now's not a good time to let your dog just be outside hanging out with all the livestock and the flies, if you can avoid it. Why take the risk?” Elden said.

Long road ahead

Although the New Mexico dog with screwworm recovered, the Texas dog was euthanized, state officials said. The Texas dog was a working dog that spent days and nights with its herd.

In the past, agricultural officials eradicated screwworm by releasing millions of sterile flies to prevent it reproducing. Controlling the new outbreak could take time, however.

“This is going to be with us for a while,” Elden said.