FIRST ARTICLE: First
case of highly pathogenic avian influenza transmitted from cow to human
confirmed
Texas Tech University
Texas Tech University's Biological Threat Research
Laboratory (BTRL) played a key role in detecting the first case of highly
pathogenic avian influenza (HPAI) A (H5N1) transmitted from a mammal (dairy
cow) to a human.
The case was made public in an article published in
the New England Journal of Medicine. Steve Presley, the director of
The Institute of Environmental and Human Health (TIEHH) and the BTRL, and
Cynthia Reinoso Webb, the biological threat coordinator at TIEHH, were
co-authors on the journal publication.
The journal article explains that in March a farm worker
who reported no contact with sick or dead birds, but who was in contact with
dairy cattle, began showing symptoms in the eye and samples were collected by
the regional health department to test for potential influenza A.
Initial testing of the samples was performed at the BTRL,
which is a component of the Centers for Disease Control and Prevention (CDC)
Laboratory Response Network-Biological (LRN-B) located at TIEHH.
"It's a huge thing that the virus has jumped from
birds to mammals, dairy cows in this case, and then to humans," Presley
said. "That's why this paper in the New England Journal of
Medicine is very significant. It's going to lay the foundation, I
believe, for a lot of research in the future of how the virus is
evolving."
The involvement of Texas Tech's BTRL is a continuation of
the partnership between regional, state and federal public health partners.
"Being part of the CDC LRN-B, we have the standing
capability to test for a lot of biological threats and some that are considered
emergent," Reinoso Webb explained.
The lab's standby status allowed Reinoso Webb and the
Texas Tech BTRL team to respond quickly to the needs of the regional public
health authority. Knowing the potential dangers of the virus, Reinoso Webb
pushed the testing into the safest laboratory available, and the team went to
work.
Having received the samples in the early evening, results
were being reported to regional, state and federal levels within hours. By the
next day the samples were on their way to the CDC for further testing and
confirmation.
"We were on the phone with the CDC until around
midnight discussing different scenarios and follow up requirements,"
Reinoso Webb said. "There is a lot of federal reporting. It was a very
complicated case, even though it was two samples and one patient.
"But we had this wonderful communication with the
CDC and made sure we did everything by the book. This is how it's been
structured, and this is how the communication was supposed to happen."
Materials provided
by Texas Tech
University. Note: Content may be edited for style and
length.
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